Antitumor phenylpropanoids found in essential oils

Carvalho AA, Andrade LN, de Sousa ÉB, de Sousa DP Biomed Research International, 2015  ABSTRACT: The search for new bioactive substances with anticancer activity and the understanding of their mechanisms of action are high-priorities in the research effort toward more effective treatments for cancer. The phenylpropanoids are natural products found in many aromatic and medicinal… Read more »

Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 Cells In Vitro and In Vivo

Lu X, Yang L, Lu C, Xu Z, Qiu H, Wu J, Wang J, Tong J, Zhu Y, Shen J BioMed Research International, 2016 ABSTRACT: Nowadays, chemotherapy is still the main effective treatment for cancer. Herb prescriptions containing Pogostemon cablin Benth (also known as “Guang-Huo-Xiang”) have been widely used in Chinese medicine today. In our… Read more »

Dietary Geraniol by Oral or Enema Administration Strongly Reduces Dysbiosis and Systemic Inflammation in Dextran Sulfate Sodium-Treated Mice

Luigia De Fazio, Enzo Spisni, Elena Cavazza, Antonio Strillacci, Marco Candela, Manuela Centanni, Chiara Ricci, Fernando Rizzello, Massimo Campieri, Maria C. Valerii Frontiers in pharmacology, 2016 ABSTRACT: (Trans)-3,7-Dimethyl-2,6-octadien-1-ol, commonly called geraniol (Ge-OH), is an acyclic monoterpene alcohol with well-known anti-inflammatory, antitumoral, and antimicrobial properties. It is widely used as a preservative in the food industry… Read more »