Cytotoxic and genotoxic potential of geraniol in peripheral blood mononuclear cells and human hepatoma cell line (HepG2)

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Queiroz TB, Santos GF, Ventura SC, Hiruma-Lima CA, Gaivão IOM, Maistro EL Genetics and Molecular Research, 2017 ABSTRACT: Geraniol is an acyclic monoterpene alcohol present in the essential oil of many aromatic plants and is one of the most frequently used molecules by the flavor and fragrance industries. The literature also reports its therapeutic potential, highlighting itself… Read more »

Cytotoxicity and genotoxicity of zingiberene on different neuron cell lines in vitro

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Togar B, Turkez H, Tatar A, Hacimuftuoglu A, Geyikoglu F Cytotechnology, 2015 ABSTRACT: The main objective of this study is to investigate the cytotoxic, genotoxic and antioxidant properties of zingiberene (ZBN) in an in vitro rat brain cell culture study. The cytotoxic effect was determined against the rat neuron and N2a neuroblastoma (N2a-NB) cell lines… Read more »

The eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage

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Dörsam B, Wu CF, Efferth T, Kaina B, Fahrer J Archives of toxicology, 2015 ABSTRACT: The natural compound 1,8-cineol, also known as eucalyptol, is a major constituent of eucalyptus oil. This epoxy-monoterpene is used as flavor and fragrance in consumer goods as well as medical therapies. Due to its anti-inflammatory properties, 1,8-cineol is also applied… Read more »