Wu H, Fu CC, Yu DD, Feng JT, Zhang X, Ma ZO
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2013
ABSTRACT:
BACKGROUND:
The main ingredient of most repellents on the market is DEET, an effective compound that has the disadvantages of toxic reactions as well as damaging effects on plastic and synthetic fabric. DEET alternatives are urgently needed.
METHODS:
The repellent activities of 11 kinds of essential oils were tested against Aedes albopictus Skuse by a Y-tube olfactometer. Using essential oils with high repellent activity as core material and gelatin and gum arabic as wall materials, we prepared microcapsules of essential oilsand optimized the preparation process. The microcapsule formulation was then subjected to repellent bioassay on hand skin.
RESULTS:
when the dosage of essential oils was 5 µL, the cinnamon oil repellent rate was 87.5% within 10 min and the Herba Schizonepetae oil(HSO) repellent rate was 98.0% within 3 min. Up to 1.5% (w/v) gelatin and 1.5% (w/v) gum arabic (as wall materials), and HSO (as core material) were used to form microcapsules with a 1:1 ratio of core material to wall material.
CONCLUSION:
The ointment preparations effectively protected hand skin exposed to a high-density A. albopictus Skuse rearing cage for 4-5 h. The HSO microcapsule repellent has broad application and development prospects.
CITATION:
Wu H, Fu CC, Yu DD et al. Repellent activity screening of 11 kinds of essential oils against Aedes albopictus Skuse: microcapsule preparation of Herba Schizonepetae oil and repellent bioassay on hand skin. Trans R Soc Trop Med Hyg. 2013;107(8):471-479.
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