Structure-activity modelling of essential oils, their components, and key molecular parameters and descriptors

Owen L, Laird K, Wilson PB Molecular and Cellular Probes, 2017 ABSTRACT: Many essential oil components are known to possess broad spectrum antimicrobial activity, including against antibiotic resistant bacteria. These compounds may be a useful source of new and novel antimicrobials. However, there is limited research on the structure-activity relationship (SAR) of essential oil compounds,… Read more »

Effects of patchouli and cinnamon essential oils on biofilm and hyphae formation by Candida species

Farisa Banu S, Rubini D, Shanmugavelan P, Murugan R, Gowrishankar S, Karutha Pandian S, Nithyanand P Journal de Mycologie Medicale, 2018 ABSTRACT: The prevalence and fatality rates with biofilm-associated candidal infections have remained a challenge to the medical fraternity despite major advances in the field of antifungal therapy. Traditionally, essential oils (EOs) from the aromatic… Read more »

Phytochemical profiles, and antimicrobial and antioxidant activities of greater galangal [Alpinia galanga (Linn.) Swartz.] flowers

Tang X, Xu C, Yagiz Y, Simonne A, Marshall MR Food Chemistry, 2018 ABSTRACT: Previous studies of galangal (Alpinia galanga) have focussed mostly on rhizomes but seldom on flowers. A comprehensive look at galangal flowers could reveal additional benefits. The chemical composition of galangal flowers was significantly (p < 0.05) different from that of galangal rhizome. Pentadecane… Read more »

Solid Lipid Nanoparticles (SLN) carrying Eugenia caryophyllata essential oil: The novel nanoparticulate systems with broad-spectrum antimicrobial activity

Fazly Bazzaz BS, Khameneh B, Namazi N, Iranshahi M, Davoodi D, Golmohammadzadeh S Letters in Applied Microbiology, 2018 ABSTRACT: In the present study, solid lipid nanoparticles containing Eugenia caryophyllata essential oil (SLN-EO) were prepared by high-shear homogenization and ultrasound methods, and used to eradicate pathogens. SLN formulations were evaluated for their size, zeta potential and… Read more »

Lemongrass essential oil and citral inhibit Src/Stat3 activity and suppress the proliferation/survival of small-cell lung cancer cells, alone or in combination with chemotherapeutic agents

Maruoka T, Kitanaka A, Kubota Y, Yamaoka G, Kameda T, Imataki O, Dobashi H, Bandoh S, Kadowaki N, Tanaka T International Journal of Oncology, 2018 ABSTRACT: Small-cell lung cancer (SCLC) is intractable due to its high propensity for relapse. Novel agents are thus needed for SCLC treatment. Lemongrass essential oil (LG-EO) and its major constituent,… Read more »

Antinociceptive Activity of Inula britannica L. and Patuletin: In vivo and Possible Mechanisms Studies

Zarei M, Mohammadi S, Komaki A Journal of Ethnopharmacology, 2018 ABSTRACT: ETHNOPHARMACOLOGICAL RELEVANCE: INULA BRITANNICA: L. (IBL) is a predominant medicinal plant traditionally utilized in the treatments of arthritis and back pain in Iranian folk medicine. AIM OF THE STUDY: The purpose of this research was to evaluate the analgesic effects of Inula britannica L…. Read more »

Busulfan-mediated oxidative stress and genotoxicity decrease in sperm of Satureja Khuzestanica essential oil-administered mice

Nasimi P, Tabandeh MR, Roohi S Systems Biology in Reproductive Medicine, 2018 ABSTRACT: Here, we studied the protective effects of Satureja Khuzestanica essential oil (SKEO) as a potent anti-oxidant, against damage caused by chemotherapy with busulfan in testis and epididymal sperm of adult mice. The NMRI adult mice were assigned: G1: control, G2: was treated… Read more »

Cananga odorata essential oil reverses the anxiety induced by 1-(3-chlorophenyl) piperazine through regulating the MAPK pathway and serotonin system in mice

Zhang N, Zhang L, Feng L, Yao L Journal of Ethnopharmacology, 2018 ABSTRACT: ETHNOPHARMACOLOGICAL RELEVANCE: Cananga odorata essential oil, known as ylang-ylang essential oil (YYO), was commonly used in the aromatherapy for relaxation and mood adjusting use. In our previous study, YYO played anxiolytic effects on the mice in several behavioral tests that based on… Read more »

Use of micronucleus and comet assay to evaluate evaluate the genotoxicity of oregano essential oil (Origanum vulgare l. Virens) in rats orally exposed for 90 days

Llana-Ruiz-Cabello M, Puerto M, Maisanaba S, Guzmán-Guillén R, Pichardo S, Cameán AM Journal of Toxicology and Environmental Health Part A, 2018 ABSTRACT: Essential oils from Origanum spp. exhibit antioxidant and antimicrobial activities making them suitable for use as food additives. The incorporation of oregano essential oil in active food packaging is under study; however, it… Read more »

The antifungal activity of essential oil from Melaleuca leucadendra (L.) L. grown in China and its synergistic effects with conventional antibiotics against Candida

Zhang J, Wu H, Jiang D, Yang Y, Tang W, Xu K Natural Product Research, 2018 ABSTRACT: To identify the natural antifungal agents, the antifungal activities of Melaleuca leucadendra (L.) L. essential oil (ML-EO) from Fujian Province of China were assayed. Treatment of ML-EO in combination with the front-line using antibiotics against Candida led to… Read more »