Nervous System

This system includes the brain, spinal cord, sensory receptors and peripheral nerves. Disorders include strokes, dementia, Alzheimer’s, Huntington’s, Parkinson’s, ADHD, epilepsy, anxiety disorders, mood disorders and stress.

Tetraclinis articulata essential oil mitigates cognitive deficits and brain oxidative stress in an Alzheimer’s disease amyloidosis model

Sadiki FZ, Idrissi ME, Cioanca O, Trifan A, Hancianu M, Hritcu L, Postu PA Phytomedicine, 2018 ABSTRACT: BACKGROUND: Tetraclinis articulata is used in traditional medicine and has been reported to possess antibacterial, antifungal, cytotoxic, anti-inflammatory and antioxidant properties. PURPOSE: This study investigated the effects of T. articulata essential oil on memory and brain oxidative stress… Read more »

Protective effect of essential oil from Citrus limon against aspirin-induced toxicity in rats

Bouzenna H, Samout N, Dhibi S, Mbarki S, Akermi S, Khdhiri A, Elfeki A, Hfaiedh N Human & Experimental Toxicology, 2018 ABSTRACT: The present study is planned to examine the antioxidant activity (AA) and the protective effect of the essential oil of Citrus limon (EOC) against aspirin-induced histopathological changes in the brain, lung, and intestine… Read more »

Aloysia citriodora Palau (lemon verbena) for insomnia patients: A randomized, double-blind, placebo-controlled clinical trial of efficacy and safety

Afrasiabian F, Mirabzadeh Ardakani M, Rahmani K, Azadi NA, Alemohammad ZB, Bidaki R, Karimi M, Emtiazy M, Hashempur MH Phytotherapy Research, 2018 ABSTRACT: Aloysia citriodora (A. citriodora) has a long history of traditional use for sedation and treatment of insomnia in different societies. This study was carried out to assess the efficacy of A. citriodora… Read more »

Effectiveness of Silexan oral lavender essential oil compared to inhaled lavender essential oil aromatherapy for sleep in adults: a systematic review

Greenberg MJ, Slyer JT JBI Database of Systematic Reviews and Implementation Reports, 2018 ABSTRACT: OBJECTIVE: The objective of the review was to identify the effectiveness of Silexan oral lavender essential oil compared to inhaled lavender essential oil aromatherapy for sleep latency, sleep duration, sleep quality, disturbed sleep and anxiety in adult patients. INTRODUCTION: Insomnia is… Read more »

Anti-depressive-like effect of 2-phenylethanol inhalation in mice

Ueno H, Shimada A, Suemitsu S, Murakami S, Kitamura N, Wani K, Matsumoto Y, Okamoto M, Ishihara T Biomedicine & Pharmacotherapy, 2018 ABSTRACT: Rose oil has traditionally been used to treat psychiatric disorders, but the scientific basis of this treatment remains poorly understood. The main odor component of rose oil is 2-phenylethanol (2-PE), but the… Read more »

Safranal protects against beta-amyloid peptide-induced cell toxicity in PC12 cells via MAPK and PI3 K pathways

Rafieipour F, Hadipour E, Emami SA, Asili J, Tayarani-najaran Z Metabolic Brain Disease, 2018 ABSTRACT: Alzheimer’s disease is a type of cerebrovascular problem with progressive mental disabilities for the patient. This study aimed to investigate the protective effect of safranal on toxicity and oxidative damage induced by beta-amyloid (Aβ) and hydrogen peroxide (H2O2) in PC12… Read more »

Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats

Akinyemi AJ, Adeniyi PA Journal of Toxicology, 2018 ABSTRACT: Studies have revealed that anti-inflammatory agents could provide beneficial effect in lowering the incidence/progression of neurological diseases. Hence, this study sought to investigate the effect of essential oils from Nigeria ginger and turmeric rhizomes on some cytokines in cadmium induced neurotoxicity. The result revealed that essential… Read more »

Agarwood Essential Oil Ameliorates Restrain Stress-Induced Anxiety and Depression by Inhibiting HPA Axis Hyperactivity

Wang S, Wang C, Yu Z, Wu C, Peng D, Liu X, Liu Y, Yang Y, Guo P, Wei J International Journal of Molecular Sciences, 2018 ABSTRACT: In our previous investigation, we found that agarwood essential oil (AEO) has a sedative-hypnotic effect. Sedative-hypnotic drugs usually have an anxiolytic effect, where concomitant anxiety and depression are a common… Read more »

Lavandula angustifolia Essential Oil and Linalool Counteract Social Aversion Induced by Social Defeat

Caputo L, Reguilon MD, Mińarro J, De feo V, Rodriguez-arias M Molecules, 2018 ABSTRACT: Many vegetable extracts, essential oils, and their main constituents are active on the Central Nervous System (CNS). In fact, they have been used as sedatives, hypnotics, or tranquilizers for their activity in treating CNS disorders. In this research, we studied the… Read more »