Hamad KJ, Al-Shaheen SJA, Kaskoos RA, Ahamad J, Mir SR
International Research Journal of Pharmacy, 2013
The essential oil of Lavandula angustifolia Mill. growing spontaneously in Iraq was investigated by GC and GC/MS for the first time. The oil was extracted from the flowers by hydro-distillation. Thirty-four components amounting to 98.91 % of the oil were identified. The major component being linalool (24.63 %). The other significant constituents were camphor (13.58 %), linalyl acetate (8.89 %), (Z)-β-ocimene (7.59 %), 1,8-cineole (7.14 %), borneol (6.41 %), (E)-β-ocimene (4.76 %), hotrienol (4.42 %), hexyl butyrate (2.96 %), α-bisabolol (1.13 %) and caryophyllene oxide (1.02 %). The strong antioxidant activity of L. angustifolia oil was also examined using the stable 2,2-diphenyl-1-picrylhydrazyl-hydrate (DPPH) free radical scavenging method. Antioxidant activity of the oil was expressed as percentage of DPPH radical inhibition and IC50 values (μg/ml). Values of percentage inhibition ranged from 3.28 to 88.91% for 7.81 μg/ml and 1000 μg/ml, respectively with an IC50 value of 216 μg/ml for oil. The results suggest the use of lavender oil as effective natural antioxidants.
Hamad KJ, Al-Shaheen SJA, Kaskoos RA, et al. Essential oil composition and antioxidant activity of Lavandula angustifolia from Iraq. Int Res J Pharm. 2013;4(4):117-120.