Transcriptomic approach and membrane fatty acid analysis to study the response mechanisms of Escherichia coli to thyme essential oil, carvacrol, 2-(E)-hexanal and citral exposure

Siroli L, Braschi G, De jong A, Kok J, Patrignani F, Lanciotti R Journal of Applied Microbiology, 2018 ABSTRACT: AIMS: The application of essential oils (EOs) and their components as food preservatives is promising but requires a deeper understanding of their mechanisms of action. This study aims to evaluate the effects of thyme EO, carvacrol,… Read more »

Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial

Ying J, Zhou MJ, Chen HY, Chen L, Zhang W, Ji J, Yu C, Zhang ZJ Chinese Journal of Integrative Medicine, 2018 ABSTRACT: OBJECTIVE: To evaluate the efficacy and safety of essential oil treatment for type III chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). METHODS: A randomized controlled trial was conducted from December 2014 to October… Read more »

Immediate and Lasting Effectsof the dōTERRA AromaTouch Technique®, a Topical Essential Oil Application Procedure, on Autonomic Function and Salivary Biomarkers: A Pilot Trial

Bahr T, Rodriguez D, Allred K Journal of Integrative Medicine & Therapy, 2018 ABSTRACT: Objectives: To explore the immediate and lasting benefits of the essential oils used in the dōTERRA AromaTouch Technique®, an essential oil application method similar to a full-body aromatherapy massage, on stress, immune secretions, inflammatory signaling, and anxiety in healthy volunteers. Design: Pilot trial…. Read more »

Gene co-expression networks in liver and muscle transcriptome reveal sex-specific gene expression in lambs fed with a mix of essential oils

Sabino M, Carmelo VAO, Mazzoni G, Cappelli K, Capomaccio S, Ajmone-Marsan P, Verini-Supplizi A, Trabalza-Marinucci M, Kadarmideen HN BMC Genomics, 2018 ABSTRACT: BACKGROUND: Essential oil (EO) dietary supplementation is a new strategy to improve animal health. EO compounds have antiparasitic, antimicrobial, antiviral, antimycotic, antioxidant and anti-inflammatory proprieties. Nutrigenomics investigations represent innovative approaches in understanding the… Read more »

Chemical Composition of Essential Oils from Thymus vulgaris, Cymbopogon citratus, and Rosmarinus officinalis, and Their Effects on the HIV-1 Tat Protein Function

Feriotto G, Marchetti N, Costa V, Beninati S, Tagliati F, Mischiati C Chemistry & Biodiversity, 2018 ABSTRACT: New drugs would be beneficial to fight resistant HIV strains, in particular those capable of interfering with essential viral functions other than those targeted by highly active antiretroviral therapy drugs. Despite the central role played by Tat protein… Read more »

Thymbra capitata (L.) Cav. and Rosmarinus officinalis (L.) Essential Oils: In Vitro Effects and Toxicity on Swine Spermatozoa

Elmi A, Ventrella D, Barone F, Filippini G, Benvenuti S, Pisi A, Scozzoli M, Bacci ML Molecules, 2017 ABSTRACT: Essential oils possess a variety of biological properties (i.e., antioxidant, antibacterial, and cytotoxic) that could possibly be applied in reproductive medicine, but their effects on spermatozoa are still partially unknown. The aim of the study was to… Read more »

Antimicrobial activity of six essential oils against Burkholderia cepacia complex: insights into mechanism(s) of action.

Perrin E, Maggini V, Maida I, Gallo E, Lombardo K, Madarena MP, Buroni S, Scoffone VC, Firenzuoli F, Mengoni A, Fani R Future Microbiology, 2018 AIM: To investigate the activity and mechanisms of action of six essential oils (EOs) against Burkholderia cepacia complex, opportunistic human pathogens highly resistant to antibiotics. MATERIALS & METHODS: Minimal inhibitory concentration of… Read more »

Essential oils of culinary herbs and spices display agonist and antagonist activities at human aryl hydrocarbon receptor AhR

Bartoňková I, Dvořák Z Food Chemistry & Toxicology ABSTRACT: Essential oils (EOs) of culinary herbs and spices are used to flavor, color and preserve foods and drinks. Dietary intake of EOs is significant, deserving an attention of toxicologists. We examined the effects of 31 EOs of culinary herbs and spices on the transcriptional activity of human… Read more »

Essential oils as antibacterial agents against food-borne pathogens: Are they really as useful as they are claimed to be?

Santos MIS, Martins SR, Veríssimo CSC, Nunes MJC, Lima AIG, Ferreira RMSB, Pedroso L, Sousa I, Ferreira MASS Journal of Food Science and Technology, 2017 ABSTRACT: Most studies evaluating the use of essential oils (EO) as antibacterial agents focus mainly on minimal inhibitory concentrations (MIC) rather than minimal bactericidal concentrations (MBC). In this work, we compared MICs… Read more »

Construction of cell factories for high production of nerolidol in Saccharomyces cerevisiae (Chinese)

Zhang LL, Ma XL, Wang D, Yu P, Huang LQ, Zhang XL, Dai ZB Zhongguo Zhong Yao Za Zhi, 2017 ABSTRACT: Nerolidol is an important constituent of terpenoid essential oil and has excellent anti-tumor, anti-bacterial, and anti-oxidative properties. For realizing heterogenous production of nerolidol, our research firstly integrated the codon-optimized Actinidia sinensis nerolidol synthase gene (NES) into the… Read more »