Antimycobacterial Activity of Cinnamaldehyde in a Mycobacterium tuberculosis (H37Ra) Model

Sawicki R, Golus J, Przekora A, Ludwiczuk A, Sieniawska E, Ginalska G. Molecules, 2018 ABSTRACT: The purpose of the study was to evaluate the antimycobacterial activity and the possible action mode of cinnamon bark essential oil and its main constituent-cinnamaldehyde-against the Mycobacterium tuberculosis ATCC 25177 strain. Cinnamaldehyde was proved to be the main bioactive compound… Read more »

Synergistic interaction of β-caryophyllene with aromadendrene oxide 2 and phytol induces apoptosis on skin epidermoid cancer cells

Pavithra PS, Mehta A, Verma RS Phytomedicine, 2018 ABSTRACT: BACKGROUND: Pamburus missionis (Wight) Swingle (Rutaceae) is traditionally used in the treatment of swellings, chronic rheumatism, paralysis and puerperal diseases. In a previous study the authors demonstrated apoptotic activity of Pamburus missionis essential oil (EO) on A431 and HaCaT cells. The major components of EO were… Read more »

Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials

Rosato A, Carocci A, Catalano A, Clodoveo ML, Franchini C, Corbo F, Carbonara GG, Carrieri A, Fracchiolla G PLoS ONE, 2018 ABSTRACT: Mentha piperita L. essential oil (EO) is employed for external use as antipruritic, astringent, rubefacient and antiseptic. Several studies demonstrated its significant antiviral, antifungal and antibacterial properties. The aim of this work is… Read more »

Potentiating effect of beta-caryophyllene on anticancer activity of alpha-humulene, isocaryophyllene and paclitaxel

Legault J, Pichette A Journal of Pharmacy and Pharmacology, 2017 ABSTRACT: Beta-caryophyllene is a sesquiterpene widely distributed in essential oils of various plants. Several biological activities are attributed to beta-caryophyllene, such as anti-inflammatory, antibiotic, antioxidant, anticarcinogenic and local anaesthetic activities. In this work, the potentiating effect of beta-caryophyllene on the anticancer activity of alpha-humulene, isocaryophyllene and paclitaxel… Read more »

Critical synergistic concentration of lecithin phospholipids improve the antimicrobial activity of eugenol against Escherichia coli

Zhang H, Dudley EG, Harte F Applied Environmental Microbiology, 2017 ABSTRACT: In this study, the effect of individual lecithin phospholipids on the antimicrobial properties of eugenol against E. coli C600 was investigated. We tested five major phospholipids common in soy or egg lecithin (DPPC, DSPC, DPPE, DPPA and DPPS) and one synthetic cationic phospholipid (EPC 18:0). Among six phospholipids,… Read more »

Antifungal mechanism of the combination of Cinnamomum verum and Pelargonium graveolens essential oils with fluconazole against pathogenic Candida strains

Essid R, Hammami M, Gharbi D, Karkouch I, Hamouda TB, Elkahoui S, Limam F, Tabbene O Applied Microbiology and Biotechnology, 2017 ABSTRACT: The present study aimed to investigate the anti-Candida activity of ten essential oils (EOs) and to evaluate their potential synergism with conventional drugs. The effect on secreted aspartic protease (SAP) activity and the mechanism of action were also explored. The… Read more »

Effects of rosemary, thyme and lemongrass oils and their major constituents on detoxifying enzyme activity and insecticidal activity in Trichoplusia ni

Tak JH, Jovel E, Isman MB Pesticide Biochemistry and Physiology, 2017 ABSTRACT: Although there have been many reports on the synergistic interactions among the major constituents of plant essential oils regarding insecticidal activity, their underlying mechanism of synergy is poorly understood. In our previous studies, we found each of the two most abundant constituents of rosemary (Rosmarinus officinalis… Read more »

Development of kinetic model for testing antifungal effect of Thymus vulgaris L. and Cinnamomum cassia L. essential oils on Aspergillus flavus spores and application for optimization of synergistic effect

Pekmezovic M, Rajkovic K, Barac A, Senerović L, Arsic Arsenijevic V Biochemical Engineering Journal, 2015 ABSTRACT: The antifungal effect of essential oils (EOs) of Thymus vulgaris L. (EOT. vulgaris) and Cinnamomum cassia L. (EOC. cassia) against Aspergillus flavus spores was evaluated by determining minimum inhibitory concentration, minimum fungicidal concentrations and fungicidal kinetics. Kinetic model of… Read more »