Digestive System

This system includes the mouth, teeth, tongue, esophagus, stomach, small intestine, pancreas, gallbladder, liver, large intestine, rectum and anus. Common disorders include GERD (acid reflux), indigestion, gut motility disorders, ulcerative colitis, Crohn’s disease and peptic or duodenal ulcers.

Thymoquinone protects rat liver after partial hepatectomy under ischemia/reperfusion through oxidative stress and endoplasmic reticulum stress prevention

Bouhlel A, Bejaoui M, Ben Mosbah I, Hadj Abdallah N, Ribault C, Viel R, Hentati H, Corlu A, Ben Abdennebi H Clinical and Experimental Pharmacology and Physiology, 2018 ABSTRACT: Ischemia reperfusion (I/R) is associated with liver injury and impaired regeneration during partial hepatectomy (PH). The aim of this study was to investigate the effect of… Read more »

Antioxidative and Cholesterol-Lowering Effects of Lemon Essential Oil in Hypercholesterolemia-Induced Rabbits

Lee H, Woo M, Kim M, Noh JS, Song YO Preventive Nutrition and Food Science, 2018 ABSTRACT: The cholesterol-lowering and anti-atherogenic effects of lemon essential oil (LEO) were investigated and compared with the effects of limonene. Owing to their volatility, both LEO and limonene were microencapsulated before preparation of the diet (20%, w/w). Hypercholesterolemia-induced rabbits… Read more »

Gene co-expression networks in liver and muscle transcriptome reveal sex-specific gene expression in lambs fed with a mix of essential oils

Sabino M, Carmelo VAO, Mazzoni G, Cappelli K, Capomaccio S, Ajmone-Marsan P, Verini-Supplizi A, Trabalza-Marinucci M, Kadarmideen HN BMC Genomics, 2018 ABSTRACT: BACKGROUND: Essential oil (EO) dietary supplementation is a new strategy to improve animal health. EO compounds have antiparasitic, antimicrobial, antiviral, antimycotic, antioxidant and anti-inflammatory proprieties. Nutrigenomics investigations represent innovative approaches in understanding the… Read more »

Plants and Surgery: The Protective Effects of Thymoquinone on Hepatic Injury-A Systematic Review of In Vivo Studies

Tekbas A, Huebner J, Settmacher U, Dahmen U International Journal of Molecular Sciences, 2018 ABSTRACT: Multimodal treatment concepts including liver transplantation for hepatocellular carcinoma (HCC), extended resection methods and neoadjuvant chemotherapy for colorectal liver metastasis significantly improve patients’ outcome. However, surgery-induced hepatic ischemia-reperfusion injury (IRI) and chemotherapy-associated hepatotoxicity result in hepatocellular damage and compromised liver… Read more »

Spasmolytic and antidiarrheal activities of Lippia thymoides (Verbenaceae) essential oil

Menezes PMN, Oliveira HR, Brito MC, Paiva GO, Ribeiro LAA, Lucchese AM, Silva FS Natural Product Research, 2018 ABSTRACT: Lippia thymoides (‘alecrim-do-mato’ or ‘alecrim-do-campo’) is used in Brazilian folk medicine to treat various illnesses, including diarrhea. This work aimed to evaluate in vitro spasmolytic and in vivo antidiarrheal activities of the L. thymoides essential oil… Read more »

Use of micronucleus and comet assay to evaluate evaluate the genotoxicity of oregano essential oil (Origanum vulgare l. Virens) in rats orally exposed for 90 days

Llana-Ruiz-Cabello M, Puerto M, Maisanaba S, Guzmán-Guillén R, Pichardo S, Cameán AM Journal of Toxicology and Environmental Health Part A, 2018 ABSTRACT: Essential oils from Origanum spp. exhibit antioxidant and antimicrobial activities making them suitable for use as food additives. The incorporation of oregano essential oil in active food packaging is under study; however, it… Read more »

Effects of lemongrass oil and citral on hepatic drug-metabolizing enzymes, oxidative stress, and acetaminophen toxicity in rats

Li CC, Yu HF, Chang CH, Liu YT, Yao HT Journal of Food and Drug Analysis, 2018 ABSTRACT: The essential oil from a lemongrass variety of Cymbopogon flexuosus [lemongrass oil (LO)] is used in various food and aroma industry products and exhibits biological activities, such as anticancer and antimicrobial activities. To investigate the effects of… Read more »

Essential oil of Cymbopogon citratus (lemongrass) and geraniol, but not citral, promote gastric healing activity in mice

Venzon L, Mariano LNB, Somensi LB, Boeing T, de Souza P, Wagner TM, Andrade SF, Nesello LAN, da Silva LM Biomedicine & Pharmacotherapy, 2018 ABSTRACT: Cymbopogon citratus, popularly known as lemongrass, is used for the treatment of gastric, nervous and hypertensive disorders, in addition to its use in the food and pharmaceutical industries. This study… Read more »

Essential oils of culinary herbs and spices display agonist and antagonist activities at human aryl hydrocarbon receptor AhR

Bartoňková I, Dvořák Z Food Chemistry & Toxicology ABSTRACT: Essential oils (EOs) of culinary herbs and spices are used to flavor, color and preserve foods and drinks. Dietary intake of EOs is significant, deserving an attention of toxicologists. We examined the effects of 31 EOs of culinary herbs and spices on the transcriptional activity of human… Read more »

Insecticidal activity of camphene, zerumbone and α-humulene from Cheilocostus speciosus rhizome essential oil against the Old-World bollworm, Helicoverpa armigera

Benelli G, Govindarajan M, Rajeswary M, Vaseeharan B, Alyahya SA, Alharbi NS, Kadaikunnan S, Khaled JM, Maggi F Ecotoxicology and Environmental Safety, 2017 ABSTRACT: The fast-growing resistance development to several synthetic and microbial insecticides currently marketed highlighted the pressing need to develop novel and eco-friendly pesticides. Among the latter, botanical ones are attracting high research… Read more »