Search Results for: cancer

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes

Hakkim FL, Bakshi HA, Khan S, Nasef M, Farzand R, Sam S, Rashan L, Al-Baloshi MS, Abdo Hasson SSA, Jabri AA, McCarron PA, Tambuwala MM Oncotarget, 2019 ABSTRACT: Melanoma is a deadly form of malignancy and according to the World Health Organization 132,000 new cases of melanoma are diagnosed worldwide each year. Surgical resection and… Read more »

Genoprotective Effects of Essential Oil Compounds Against Oxidative and Methylated DNA Damage in Human Colon Cancer Cells

Thapa D, Richardson AJ, Zweifel B, Wallace RJ, Gratz SW Journal of Food Science, 2019 ABSTRACT: Essential oils (EO) are widely used in foods as flavoring and preservative agents. Many of the biological activities of EO have been attributed to major essential oil compounds (EOC) but their direct interaction with colonic epithelial cells and their… Read more »

Essential Oil Compound, Patchouli Alcohol, Represses Tumor Formation in Vivo and Causes G1 Arrest by Downregulating β-catenin Transcriptional Activity in Colon Cancer Cells

Lee J, Lee SH Current Developments in Nutrition, 2019 ABSTRACT: OBJECTIVES: Patchouli alcohol is one of the abundant compounds isolated from essential oil of Pogostemon cablin and shows anti-inflammatory, anti-obese and anti-cancer activities. The current study was designed to investigate if treatment of patchouli alcohol exhibits tumor suppressive activity in colon cancer mouse model and… Read more »

Chemoprevention of Colorectal Cancer by Dietary Compounds

Costea T, Hudiță A, Ciolac OA, Gălățeanu B, Ginghină O, Costache M, Ganea C, Mocanu MM International Journal of Molecular Sciences, 2018 ABSTRACT: Colorectal cancer is one of the leading causes of death, and the third most diagnosed type of cancer, worldwide. It is most common amongst men and women over 50 years old. Risk… Read more »

Induction of apoptosis by essential oil from P. missionis in skin epidermoid cancer cells

Pavithra PS, Mehta A, Verma RS Phytomedicine, 2018 ABSTRACT: BACKGROUND: The genus Pamburus (Rutaceae) comprises the only species, Pamburus missionis (Wight) Swingle. Pamburus missionis is traditionally used in the treatment of swellings, chronic rheumatism, paralysis and puerperal diseases. PURPOSE: The present study investigates the cancer chemotherapeutic potential of essential oil (EO) from P. missionis. METHODS:… Read more »

Anti-proliferative activity of Origanum vulgare inhibited lipogenesis and induced mitochondrial mediated apoptosis in human stomach cancer cell lines

Balusamy SR, Perumalsamy H, Huq MA, Balasubramanian B Biomedicine and Pharmacotherapy, 2018 ABSTRACT: Origanum vulgare commonly known as oregano belongs to mint family (Laminaceae), and native to temperate western and mediterranean region. In our present study, we have identified the bio-active principles of oregano essential oil (EO) and evaluated its apoptotic effects against human stomach… Read more »

Terpenes from essential oils and hydrolate of Teucrium alopecurus triggered apoptotic events dependent on caspases activation and PARP cleavage in human colon cancer cells through decreased protein expressions

Guesmi F, Tyagi AK, Prasad S, Landoulsi A Oncotarget, 2018 ABSTRACT: This study focused on characterizing the Hydrophobic and Hydrophilic fractions of Teucrium alopecurus in the context of cancer prevention and therapy. The goal was also to elucidate the molecular mechanisms involved and to determine its efficacy against cancer by triggering apoptosis and suppressing tumorigenesis… Read more »

Anti-cancer effects of Rhizoma Curcumae against doxorubicin-resistant breast cancer cells

Zhong Z, Yu H, Wang S, Wang Y, Cui L Chinese Medicine, 2018 ABSTRACT: BACKGROUND: Chemotherapy is a primary approach in cancer treatment after routine surgery. However, chemo-resistance tends to occur with chemotherapy in clinic, resulting in poor prognosis and recurrence. Nowadays, Chinese medicine may shed light on design of new therapeutic modes to overcome… Read more »

Synergistic interaction of β-caryophyllene with aromadendrene oxide 2 and phytol induces apoptosis on skin epidermoid cancer cells

Pavithra PS, Mehta A, Verma RS Phytomedicine, 2018 ABSTRACT: BACKGROUND: Pamburus missionis (Wight) Swingle (Rutaceae) is traditionally used in the treatment of swellings, chronic rheumatism, paralysis and puerperal diseases. In a previous study the authors demonstrated apoptotic activity of Pamburus missionis essential oil (EO) on A431 and HaCaT cells. The major components of EO were… Read more »

The Use of Aromatherapy to Reduce Chemotherapy-Induced Nausea in Children With Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial

Evans A, Malvar J, Garretson C, Pedroja kolovos E, Baron nelson M Journal of Pediatric Oncology Nursing, 2018 ABSTRACT: INTRODUCTION: Chemotherapy-induced nausea can be distressing and difficult to manage in children with cancer. The purpose of this study was to investigate the utility of ginger aromatherapy in relieving chemotherapy-induced nausea in children with cancer. METHOD:… Read more »