Search Results for: cancer

Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 Cells In Vitro and In Vivo

Lu X, Yang L, Lu C, Xu Z, Qiu H, Wu J, Wang J, Tong J, Zhu Y, Shen J BioMed Research International, 2016 ABSTRACT: Nowadays, chemotherapy is still the main effective treatment for cancer. Herb prescriptions containing Pogostemon cablin Benth (also known as “Guang-Huo-Xiang”) have been widely used in Chinese medicine today. In our… Read more »

Chemical composition and in vitro evaluation of antioxidant, antimicrobial, cytotoxicity and anti-acetylcholinesterase properties of Tunisian Origanum majorana L. essential oil

Hajlaoui H, Mighri H, Aouni M, Gharsallah N, Kadri A Microbial pathogenesis, 2016 ABSTRACT: This study investigated the chemical composition and evaluated the antioxidant, antimicrobial, cytotoxic and anti-acetylcholinesterase properties of Tunisian Origanum majorana essential oil. The findings showed that the oil exhibited high activity, particularly in terms of reducing power and β-Carotene bleaching, inducing higher… Read more »

Cytotoxicity and genotoxicity of zingiberene on different neuron cell lines in vitro

Togar B, Turkez H, Tatar A, Hacimuftuoglu A, Geyikoglu F Cytotechnology, 2015 ABSTRACT: The main objective of this study is to investigate the cytotoxic, genotoxic and antioxidant properties of zingiberene (ZBN) in an in vitro rat brain cell culture study. The cytotoxic effect was determined against the rat neuron and N2a neuroblastoma (N2a-NB) cell lines… Read more »

The eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage

Dörsam B, Wu CF, Efferth T, Kaina B, Fahrer J Archives of toxicology, 2015 ABSTRACT: The natural compound 1,8-cineol, also known as eucalyptol, is a major constituent of eucalyptus oil. This epoxy-monoterpene is used as flavor and fragrance in consumer goods as well as medical therapies. Due to its anti-inflammatory properties, 1,8-cineol is also applied… Read more »