Cortellini A, Verna L, Cannita K, Napoleoni L, Parisi A, Ficorella C, Porzio G Indian Journal of Palliative Care, 2017 ABSTRACT: Chemotherapy-induced peripheral neuropathy is a frequent treatment-limiting factor that significantly impairs patients’ everyday life, also because of a lack of valid palliative options. Here, we report a case of a male patient with a history of metastatic… Read more »
Search Results for: cancer
Cytotoxicity of the Essential Oil of Fennel (Foeniculum vulgare) from Tajikistan
Sharopov F, Valiev A, Satyal P, Gulmurodov I, Yusufi S, Setzer WN, Wink M Foods, 2017 ABSTRACT: The essential oil of fennel (Foeniculum vulgare) is rich in lipophilic secondary metabolites, which can easily cross cell membranes by free diffusion. Several constituents of the oil carry reactive carbonyl groups in their ring structures. Carbonyl groups can… Read more »
Antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities of the essential oil of Psidium guineense Sw. and spathulenol
do Nascimento KF, Moreira FMF, Alencar Santos J, Kassuya CAL, Croda JHR, Cardoso CAL, Vieira MDC, Góis Ruiz ALT, Ann Foglio M, de Carvalho JE, Formagio ASN Journal of Ethnopharmacology, 2017 ETHNOPHARMACOLOGICAL RELEVANCE: Leaves from Psidium guineense Sw. are used in popular medicine for the treatment of inflammatory disease. However, there is no scientific evidence… Read more »
Thymoquinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells
Gurung RL, Lim SN, Khaw AK, Soon JF, Shenoy K, Mohamed Ali S, Jayapal M, Sethu S, Baskar R, Hande MP PloS One, 2010 ABSTRACT: BACKGROUND: A major concern of cancer chemotherapy is the side effects caused by the non-specific targeting of both normal and cancerous cells by therapeutic drugs. Much emphasis has been placed on discovering new compounds that target tumour cells more… Read more »
Clove extract functions as a natural fatty acid synthesis inhibitor and prevents obesity in a mouse model
Ding Y, Gu Z, Wang Y, Wang S, Chen H, Zhang H, Chen W, Chen YQ Food & Function, 2017 ABSTRACT: Numerous medicinal plants have been reported to prevent various chronic diseases. In this study, we screened a new FASN inhibitor-alcohol extract of clove (AEC) using a fast microplate method developed in our laboratory. The major components of AEC were: eugenol (42.27%), acetyl eugenol (29.12%), caryophyllene (15.40%), and… Read more »
Antifungal and Ichthyotoxic Sesquiterpenoids from Santalum album Heartwood
Kim TH, Hatano T, Okamoto K, Yoshida T, Kanzaki H, Arita M, Ito H Molecules, 2017 ABSTRACT: In our continuing study on a survey of biologically active natural products from heartwood of Santalum album (Southwest Indian origin), we newly found potent fish toxic activity of an n-hexane soluble extract upon primary screening using killifish (medaka) and characterized α-santalol and β-santalol as the active components. The toxicity… Read more »
β-elemene regulates endoplasmic reticulum stress to induce the apoptosis of NSCLC cells through PERK/IRE1α/ATF6 pathway
Liu Y, Jiang ZY, Zhou Y, Qiu HH, Wang G, Luo Y, Liu JB, Liu XW, Bu WQ, Song J, Cui L, Jia XB, Feng L Biomedicine & Pharmacotherapy, 2017 ABSTRACT: Endoplasmic reticulum stress (ERs) has been regarded as an important cause for the pathogenesis of non-small-cell lung cancer (NSCLC). β-elemene is an active component in the essential oil extracted from a medicinal herb, Curcuma wenyujin, and has been… Read more »
Essential Oils of Oregano: Biological Activity beyond Their Antimicrobial Properties
Leyva-López N, Gutiérrez-Grijalva EP, Vazquez-Olivo G, Heredia JB Molecules, 2017 ABSTRACT: Essential oils of oregano are widely recognized for their antimicrobial activity, as well as their antiviral and antifungal properties. Nevertheless, recent investigations have demonstrated that these compounds are also potent antioxidant, anti-inflammatory, antidiabetic and cancer suppressor agents. These properties of oregano essential oils are of potential interest to the food,… Read more »
Phytochemical and pharmacological properties of essential oils from Cedrus species
Saab AM, Gambari R, Sacchetti G, Guerrini A, Lampronti I, Tacchini M, El Samrani A, Medawar S, Makhlouf H, Tannoury M, Abboud J, Diab-Assaf M, Kijjoa A, Tundis R, Aoun J, Efferth T Natural Product Research, 2017 ABSTRACT: Natural products frequently exert pharmacological activities. The present review gives an overview of the ethnobotany, phytochemistry and pharmacology of the Cedrus genus, e.g. cytotoxic, spasmolytic immunomodulatory, antiallergic, anti-inflammatory and analgesic activities. Cancer… Read more »
Aromatherapy and Essential Oils (PDQ®): Health Professional Version
PDQ Integrative, Alternative, and Complementary Therapies Editorial Board PDQ Cancer Information Summaries, 2017 EXCERPT: This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the use of aromatherapy and essential oils in the treatment of people with cancer. It is intended as a resource to inform and assist clinicians who care for cancer… Read more »